Their fight ends when the motel manager calls the police on them. In the morning at breakfast, Meg tells Kate they should stop ruining their friendship over a guy, but when Meg lets slip that Ryan has a misshaped penis, something Kate had seen from having sex with him, Kate realizes Meg had sex with Ryan as well and reaches breaking point with her, with the two getting into a physical fight over their issues with each other, Meg's selfishness and Kate's unwillingness to take chances, making a mess of the motel lobby in the process. Back at the hotel, Ryan makes a pass at Kate, who gives in and has rigorous sex with him. When Craig fails to impress Meg, he suggests to her that she should be open to the qualities of other guys. Meg decides to go to a local bar where Craig joins her. Meg says that she can have Ryan, but Kate proclaims she never wanted Ryan, just that she didn't want Meg to have him. When Kate sees the pills in the bottle, she asks for a hotel room for herself. After a few hours, Craig eventually passes out and crashes the car, forcing the four to spend the night at a motel. When Kate declines to drink, Craig, who is driving, takes it instead, much to Meg's horror. Back in the car, Kate fakes an injury to get a massage from Ryan, prompting Meg to put sleeping pills into a bottle of wine to give to Kate. Kate shows embarrassing childhood photos of Meg to the guys for their amusement and in response, Meg locks Kate in a messy gas station bathroom, forcing Kate to escape through a high window covered in feces. When it is learned the hurricane will move away from Florida, Ryan is able to get a ride from Craig (Matt Jones), a jewelry salesman who had taken a liking to Meg but had been continually rebuffed by her, and the girls ask to tag along. Their following day is unfortunate when during their ride in a hot air balloon, Kate is having a panic attack due to fear of heights and Meg accidentally pops a champagne cork into the only eye of the one-eyed pilot and Meg ends up injuring her eye after a risky flip into the swimming pool. Before going to bed, Kate tells Meg that she will fight her for Ryan's affections. When Ryan learns the hurricane will delay his trip even further, the girls attempt to cheer him up with a dance competition.
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The girls are taken to the local Sheraton Hotel and bump into Ryan, who invites them to drinks and the hotel club. Louis due to a hurricane warning in the Florida area. A few hours into the flight, the plane is diverted to St. Both Kate and Meg are immediately attracted to him and begin to shamelessly flirt with him, but Kate eventually passes out having taken too many anti-anxiety pills. The middle seat is eventually occupied by Ryan (Matt Barr), a handsome firefighter on his way to a wedding. Barely making it to their flight on time, Kate is put in a window seat and Meg gets an aisle seat. The reserved Kate is reluctant, but ultimately acquiesces as Meg had already booked non-refundable tickets to Fort Lauderdale using Kate's frequent flyer miles. After a night of drinking away their stress, the adventurous Meg suggests they go on vacation to get their groove back. Meg is a cosmetics saleswoman trying and failing to sell beauty products. Kate is a high school English teacher, bored of her regular curriculum and under pressure to quit by Principal Moss (Rob Corddry) who believes she should be in a different profession.